Infanrix Hexa Description

The diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliomyelitis (DTPa-HBV-IPV) component is a turbid white suspension.
The lyophilised Haemophilus influenzae type b (Hib) component is a white powder.
After reconstitution, 1 dose (0.5 ml) contains: Diphtheria toxoid¹ not less than 30 International Units (IU).
Tetanus toxoid¹ not less than 40 International Units (IU).
Bordetella pertussis antigens: Pertussis toxoid (PT)¹ 25 micrograms; Filamentous Haemagglutinin (FHA)¹ 25 micrograms; Pertactin (PRN)¹ 8 micrograms.
Hepatitis B surface antigen (HBs)^2,3 10 micrograms.
Poliovirus (inactivated) (IPV): type 1 (Mahoney strain)⁴ 40 D-antigen unit; type 2 (MEF-1 strain)⁴ 8 D-antigen unit; type 3 (Saukett strain)⁴ 32 D-antigen unit.
Haemophilus influenzae type b polysaccharide (polyribosylribitol phosphate, PRP)³ 10 micrograms, conjugated to tetanus toxoid as carrier protein approximately 25 micrograms.
¹adsorbed on aluminium hydroxide, hydrated (Al(OH)₃) 0.5 milligrams Al³⁺.
²produced in yeast cells (Saccharomyces cerevisiae) by recombinant DNA technology.
³adsorbed on aluminium phosphate (AlPO₄) 0.32 milligrams Al³⁺.
⁴propagated in VERO cells.
The vaccine may contain traces of formaldehyde, neomycin and polymyxin which are used during the manufacturing process (see Contraindications).
Excipients/Inactive Ingredients: Hib powder: Lactose anhydrous.
DTPa-HBV-IPV suspension: Sodium chloride (NaCl); Medium 199 containing principally amino acids, mineral salts, vitamins; Water for injections.